Cell-surface class I major histocompatibility complex (MHC) molecules present processed self-and nonself-peptides to thymus-derived (T) lymphocytes, allowing the intracellular compartment of cells to be sampled in order to detect infection. Since the class I MHC-peptide complex plays a critical role
✦ LIBER ✦
A biological function for the XP motif within the N terminus of major histocompatibility complex class II-associated peptides
✍ Scribed by Minka Breloer; Svenja Ehrlich; Bernhard Fleischer; Arne von Bonin
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 477 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0014-2980
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## Abstract ## Objective Although studies have suggested that human cartilage (HC) gp‐39 may be an antigen recognized by autoreactive CD4+ T cells in rheumatoid arthritis, we previously failed to identify specific CD4+ T cells in patients' synovial fluid or blood using a class II major histocompat