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PCR-assisted localization of the human SRPR gene

โœ Scribed by Nicolas Janin; Oliver Delattre; Marc Lipinski

Publisher
Springer
Year
1992
Tongue
English
Weight
298 KB
Volume
88
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

A polymerase chain reaction (PCR)-based assay has been designed that detects the presence of the human signal recognition particle receptor (SRPR) gene in inter-species somatic cell hybrids. By using hybrids containing various fragments of chromosome 11q, SRPR has been mapped to a chromosomal region flanked by the 11q23 and 11q24 breakpoints associated with the constitutional and neuroepithelioma (11;22) translocations, respectively.

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