A novel dopamine D3 receptor gene that may be involved in psychiatric diseases has recently been characterized. It has been assigned to chromosome 3 by hybridization with a D3 receptor probe to human sorted chromosomes, and localized to band 3q 13.3 by in situ hybridization.
Chromosomal localization of the human histamine H1-receptor gene
โ Scribed by Maryvonne Coniat; Elisabeth Traiffort; Martial Ruat; Jean-Michel Arrang; Roland Berger
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 231 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0340-6717
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โฆ Synopsis
We have assigned the human histamine H1-receptor gene to chromosome 3 by Southern blot analysis of a chromosome mapping panel constructed from human-hamster somatic cell hybrids. This assignment was confirmed by in situ hybridization on metaphase chromosomes and involved bands 3p14-p21.
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