๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Structure and chromosomal localization of the human lymphotoxin gene

โœ Scribed by Glenn E. Nedwin; Julie Jarrett-Nedwin; Douglas H. Smith; Susan L. Naylor; Alan Y. Sakaguchi; David V. Goeddel; Patrick W. Gray

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
592 KB
Volume
29
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

โœฆ Synopsis

We have isolated, sequenced, and determined the chromosomal localization of the gene encoding human lymphotoxin (LT). The single copy gene was isolated from a human genomic library using a "P-labeled 116 bp synthetic DNA fragment whose sequence was based on the NHz-terminal amino acid sequence of LT. The gene spans 3 kb of DNA and is interrupted by three intervening sequences. The LT gene is located on human chromosome 6, as determined by Southern blot analysis of human-murine hybrid DNA. Putative transcriptional control regions and areas of homology with the promoters of interferon and other genes are identified.

๐Ÿ“œ SIMILAR VOLUMES

Structure, chromosomal localization, and
Structure, chromosomal localization, and brain expression of human Cx36 gene
โœ N. Belluardo; A. Trovato-Salinaro; G. Mudรฒ; Y.L. Hurd; D.F. Condorelli ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 636 KB

Rat connexin-36 (Cx36) is the first gap junction protein shown to be expressed predominantly in neuronal cells of the mammalian central nervous system. As a prerequisite for studies devoted to the investigation of the possible role of this connexin in human neurological diseases, we report the cloni

Gene structure and chromosomal localizat
Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein
โœ Marian L. Birkeland; Neal G. Copeland; Debra J. Gilbert; Nancy A. Jenkins; A. Ne ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 600 KB

## Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein The OX40 protein is expressed only on activated rat CD4+ T blasts and is a member of a superfamily of cell surface molecules which includes CD40, CD30, CD95 (Fas), CD27, 4-1BB antigens and the receptors for t

Chromosomal localization of the human my
Chromosomal localization of the human myeloperoxidase gene by in situ hybridization using oligonucleotide probes
โœ Dr. Sharif R. Zaki; Garth E. Austin; Wing C. Chan; Ann L. Conaty; Suzanne Trusle ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 382 KB

## Abstract Oligonucleotide probes have been used to map the myeloperoxidase (__MPO__) gene locus to chromosome bands 17q21โ€“22. This is in agreement with results reported using conventional cDNA probes. No evidence for the existence of a second __MPO__ gene locus was obtained. Six synthetic 72โ€base

Mouse CD-RAP/MIA gene: Structure, chromo
Mouse CD-RAP/MIA gene: Structure, chromosomal localization, and expression in cartilage and chondrosarcoma
โœ Anja K. Bosserhoff; Seiji Kondo; Markus Moser; Uwe H. Dietz; Neal G. Copeland; D ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 428 KB

A cDNA encoding a novel protein has been previously isolated from two independent sources: melanoma cell cultures and chondrocytes. The protein from human melanoma cell lines and tumors is called melanoma inhibitory activity (MIA) (Blesch et al. [1994] Cancer Res. 54:5695-5701) and the protein from

Molecular characterization and chromosom
Molecular characterization and chromosomal localization of mouse Purฮฑ gene
โœ Vandhana Muralidharan; Laura Cort; Ellen Meier; Elizabeth P. Blankenhorn; Kamel ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 127 KB ๐Ÿ‘ 1 views

Purโฃ is a 39-kDa sequence-specific single-stranded DNA/RNA binding protein with the ability to modulate transcription of several genes containing the Pur element in their promoter region. Human and mouse Purโฃ exhibit an extraordinary degree of conservation with only two changes at amino acid residue