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Partial deletions of long arm of chromosome 6: biologic and clinical implications in adult acute lymphoblastic leukemia

✍ Scribed by Mancini, M; Vegna, M L; Castoldi, G L; Mecucci, C; Spirito, F; Elia, L; Tafuri, A; Annino, L; Pane, F; Rege-Cambrin, G


Book ID
110055198
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
124 KB
Volume
16
Category
Article
ISSN
0887-6924

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Deletion of a common region on the long
✍ Dr. Lia P. Menasce; Vassilis Orphanos; Mauro Santibanez-Koref; John M. Boyle; Ch πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 340 KB

We have characterised a region of deletion on the long arm of chromosome 6 (6q) in six cases of acute lymphobiastic leukaemia, by fluorescence in situ hybridisation, using a series of YAC clones which map to 6q. Conventional cytogenetic analysis of four of these cases had been interpreted as showing

Common region of deletion on the long ar
✍ Lia P. Menasce; Vassilis Orphanos; Mauro Santibanez-Koref; John M. Boyle; Dr. Ch πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 253 KB

## Abstract We have used fluorescence in situ hybridisation (FISH) with a series of yeast artificial chromosome (YAC) clones that map to the long arm of chromosome 6 (6__q__) to define the region(s) of deletion in seven cases of non‐Hodgkin's lymphoma (NHL), in which a deletion of 6q had been detec