Clinical and prognostic significance of the Philadelphia chromosome in adult patients with acute lymphoblastic leukemia
✍ Scribed by G. Götz; H. -J. Weh; T. A. Walter; R. Kuse; K. Kolbe; G. Dölken; K. P. Hellriegel; D. Hoelzer; D. K. Hossfeld
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 412 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0939-5555
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Chromosome studies, using bone marrow samples of 26 pretreated children (below 15 years of age) with Acute Lymphoblastic Leukemia were carried out to explore the potentialities of applying chromosomal findings as a prognostic indicator in these patients. Abnormal karyotype was identified in 15 patie
## Abstract Acute lymphoblastic leukemia (ALL) is a heterogeneous disorder, with the greatest prevalence in children, but it also affects adults, and has an increasing incidence with age. Chromosomal abnormalities in ALL have been frequently described, the most common is the Philadelphia chromosome