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Acute lymphoblastic leukemia without the Philadelphia chromosome occurring in chronic myelogenous leukemia with the Philadelphia chromosome

โœ Scribed by Hee Jin Huh; Jung Won Huh; Chu Myong Seong; Miae Lee; Wha Soon Chung


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
49 KB
Volume
74
Category
Article
ISSN
0361-8609

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## Background: Patients with chronic myelogenous leukemia (cml) occasionally experience persistent thrombocythemia despite having adequate white blood cell (wbc) counts. trimethylenethiophosphoramide (thiotepa) is an alkylating agent that significantly inhibits platelet production. ## Methods: Th