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P a m p l o n a . SPAIN.
Recent experimental data suggest that different s t ~i a t a l efferent pathways mediate the actions of D -l and D -2 receptor subtypes in r a t s . In order to know whether this organization is a l s o evident in primates. we studied the ability of SCH 23390
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We report clinical data on six Parkinsonian patients on long term L-dopa therapy who complained of short, but clear deterioration of parkinsonian symptoms imediatly after L-dopa intake. After an oral challenge with 275mg L-dopdcarbidopa (and apomorphine 3mg SC in two cases) patients were assessed e
In 21 patienta with parkinaonism pattern reversal visual evoked potentials (YBPs) and cortical and spinal somatosensory evoked potentiala (SEPa) wrw etudied.Transit time to cortex was eatimated.Al1 of these petients were treated with L-dam preparations. The obtained data were compared with the simil
Recently, it was reported that parkinsonlan patients exhibit mitochondrial abnormalhies which might be related to the production of either endogenous or exogenous toxins. We, thus, assessed possible inhibitory effects of dopamine-related compounds on mitochondrial respiration in rat brain. We found