Parkinson's disease/Parkinson syndromes—electrophysiology

• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 109 KB
• Volume: 7
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.870070551

✦ Synopsis

In 21 patienta with parkinaonism pattern reversal visual evoked potentials (YBPs) and cortical and spinal somatosensory evoked potentiala (SEPa) wrw etudied.Transit time to cortex was eatimated.Al1 of these petients were treated with L-dam preparations. The obtained data were compared with the similar The analysis of VEPs indicated prolonpatlon of the latency of the major msitiva wave R m in 7 patients(35%).No differences were found of the RwAhzo amplitude i n the group with parkinsonism in relation to controls.Thc study of SEPs indicated the delay of latency of the cortical component N9s in 10 subJects (50X).Thcee results were statistically significant. valws in 20 healthy controls. No simificant differences were found k t w e n the patients and the controls in the transit time to cortex.

The authors discuss the possible effects of disturbed dopamine metabolism on afferent pathways in central nervous system in patients with parkinaonism.The posrrible "an-motor function of the basal ganglia is also discussed.