𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Parkinson's disease/Parkinson syndromes—Cognitive functions

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
289 KB
Volume
7
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

We have measured increment thresholds for a 4.1 cycfdeg grating in 24 de-novo patients (Hoehn and Yahr stage I to 111) with idiopathic (IPS) and 9 patients with nonidiopathic parkinson syndrome (N-IPS) and for comparison 26 age-matched normal controls.

Patients with positive L-Dopa and apomorphine response were tentatively classified as IPS, patients not responding as N-IPS. The latter encompassed 4 patients with vascular lesions in CT/MR imaging and 5 with suspected multisystem atrophy.

8/24 patients with IPS presented with unequivocal threshold enhancement. 4/24 patients with IPS and 219 patients with N-IPS showed slightly enhanced thresholds. All other patients were normal. We conclude that in the diagnosis of early IPS enhanced increment thresholds contribute in 1j3 of the IPS patients to the differentiation from nonidiopathic Parkinson syndrome.

📜 SIMILAR VOLUMES

Parkinson's disease/Parkinson syndromes—
Parkinson's disease/Parkinson syndromes—transplantation
📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 282 KB

P a m p l o n a . SPAIN. Recent experimental data suggest that different s t ~i a t a l efferent pathways mediate the actions of D -l and D -2 receptor subtypes in r a t s . In order to know whether this organization is a l s o evident in primates. we studied the ability of SCH 23390

Parkinson's disease/Parkinson syndromes—
Parkinson's disease/Parkinson syndromes—apomorphine
📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB

We report clinical data on six Parkinsonian patients on long term L-dopa therapy who complained of short, but clear deterioration of parkinsonian symptoms imediatly after L-dopa intake. After an oral challenge with 275mg L-dopdcarbidopa (and apomorphine 3mg SC in two cases) patients were assessed e

Parkinson's disease/Parkinson syndromes—
Parkinson's disease/Parkinson syndromes—electrophysiology
📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB

In 21 patienta with parkinaonism pattern reversal visual evoked potentials (YBPs) and cortical and spinal somatosensory evoked potentiala (SEPa) wrw etudied.Transit time to cortex was eatimated.Al1 of these petients were treated with L-dam preparations. The obtained data were compared with the simil