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Pancreatic Cancer || Hedgehog Signaling Pathways in Pancreatic Cancer Pathogenesis

✍ Scribed by Neoptolemos, John P.; Urrutia, Raul; Abbruzzese, James L.; Büchler, Markus W.

Book ID
127293651
Publisher
Springer New York
Year
2010
Weight
245 KB
Category
Article
ISBN
038777498X

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## Abstract Pancreatic cancer is an aggressive malignancy that exhibits a number of genetic and epigenetic alterations. Indian hedgehog (Ihh) and its 2 signaling receptors, patched (Ptc) and smoothened (Smo), are involved in pancreatic development and regulation of β‐cell function as well as in cer