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165 Hedgehog Signaling Regulates Angiogenesis in Pancreatic Cancer

✍ Scribed by Yoshiaki Sugiyama; Yusuke Mizukami; Kazumasa Nakamura; Junpei Sasajima; Tomoya Nishikawa; Kazuya Koizumi; Mikihiro Fujiya; Satoshi Tanno; Toshikatsu Okumura; Toru Kono; Daniel Chung; Yutaka Kohgo

Book ID
119430005
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
107 KB
Volume
136
Category
Article
ISSN
0016-5085

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## Abstract Pancreatic cancer is an aggressive malignancy that exhibits a number of genetic and epigenetic alterations. Indian hedgehog (Ihh) and its 2 signaling receptors, patched (Ptc) and smoothened (Smo), are involved in pancreatic development and regulation of β‐cell function as well as in cer