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Palladium-catalysed cross-coupling of 2-trimethylsilylpyridine with aryl halides

✍ Scribed by Spencer Napier; Sebastian M. Marcuccio; Heather Tye; Mark Whittaker

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
148 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

Palladium-catalysed cross-coupling of 2-trimethylsilylpyridine with aryl halides in the presence of stoichiometric silver(I) oxide, and catalytic TBAF allows the rapid preparation of the corresponding pyridin-2-ylaryl compounds in moderate to good yields under mild thermal conditions.

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