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p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines

✍ Scribed by K. Servomaa; A. Kiuru; R. Grénman; K. Pekkola-Heino; J. O. Pulkkinen; T. Rytömaa

Book ID
114425088
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
348 KB
Volume
29
Category
Article
ISSN
0960-7722

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## Background: A critical factor for successful organ preservation treatment in head and neck cancer may be selecting tumors that respond to chemotherapy and radiation. previous results in patients indicated that tumors that overexpressed p53 were more sensitive to chemotherapy than those that did