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Mutation of p53 in Squamous Cell Cancer of the Head and Neck: Relationship to Tumor Cell Proliferation

✍ Scribed by Nancy B. Wood; Valery Kotelnikov; David D. Caldarelli; James Hutchinson; William R. Panje; Poornima Hegde; Sue Leurgans; Suzanne LaFollette; Samuel G. Taylor; Harvey D. Preisler; John S. Coon


Book ID
110079392
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
714 KB
Volume
107
Category
Article
ISSN
0023-852X

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## Background: A critical factor for successful organ preservation treatment in head and neck cancer may be selecting tumors that respond to chemotherapy and radiation. previous results in patients indicated that tumors that overexpressed p53 were more sensitive to chemotherapy than those that did