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p53 Mutation and Locoregional Treatment Failure in Head and Neck Squamous Cell Carcinoma

✍ Scribed by Koch, W. M.; Brennan, J. A.; Zahurak, M.; Goodman, S. N.; Westra, W. H.; Schwab, D.; Yoo, G. H.; Lee, D. J.; Forastiere, A. A.; Sidransky, D.

Book ID
118144088
Publisher
Oxford University Press
Year
1996
Tongue
English
Weight
679 KB
Volume
88
Category
Article
ISSN
0027-8874

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## Background: A critical factor for successful organ preservation treatment in head and neck cancer may be selecting tumors that respond to chemotherapy and radiation. previous results in patients indicated that tumors that overexpressed p53 were more sensitive to chemotherapy than those that did