Clinical implication of screeningp53gene mutations in head and neck squamous cell carcinomas
✍ Scribed by L. Ma; A. Ronai; U. N. Riede; G. Köhler
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 186 KB
- Volume
- 124
- Category
- Article
- ISSN
- 1432-1335
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## Loss of heterozygosity (LOH ) at chromosome band 10q23 occurs frequently in a wide variety of human tumors. A recently identified candidate tumor suppressor gene, PTEN located on 10q23, is mutated in multiple advanced cancers. To explore whether PTEN is associated with human squamous cell carci
## Abstract ## __Background.__ To date, more than 60 gene expression profiling (GEP) studies have been published in the field of head and neck squamous cell carcinoma (HNSCC) with variable objectives, methods, and results. ## __Methods.__ The purpose of this study was to present a state‐of‐the‐a
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