✦ LIBER ✦

Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines

✍ Scribed by Bergman, A M; Pinedo, H M; Talianidis, I; Veerman, G; Loves, W J P; van der Wilt, C L; Peters, G J

Book ID: 109997610
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 204 KB
Volume: 88
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6601011

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Overexpression of Multidrug Resistance P

Overexpression of Multidrug Resistance Protein Gene in Human Cancer Cell Lines Selected for Drug Resistance to Epipodophyllotoxins

✍ Koike, Koji ;Abe, Tatsuya ;Hisano, Terumasa ;Kubo, Takeshi ;Wada, Morimasa ;Kohn 📂 Article 📅 1996 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 495 KB

Reduced drug accumulation and multidrug

Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression

✍ Jong Seok Lee; Stefania Scala; Yoshihito Matsumoto; Bruce Dickstein; Rob Robey; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

MCF-7 human breast cancer cells selected in Adriamycin in the presence of verapamil developed a multidrug resistant phenotype, which was characterized by as much as 100,000-fold resistance to mitoxantrone, 667-fold resistance to daunorubicin, and 600-fold resistance to doxorubicin. Immunoblot and PC

Regulation of expression of P-glycoprote

Regulation of expression of P-glycoprotein and gst by multidrug-resistant reversors in adm-sensitive and adm-resistant human tumor cell lines

✍ Zuofu Xie; Xiandong Lin; Dongmei Zhou; Sheng Lin 📂 Article 📅 1999 🏛 Chinese Anti-Cancer Association 🌐 English ⚖ 735 KB

Ritonavir induces P-glycoprotein express

Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line

✍ Michael D. Perloff; Lisa L. Von Moltke; James E. Marchand; David J. Greenblatt 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB

The present study characterized the response of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP1) to chronic ritonavir (RIT) exposure by assessing increases in P-gp and MRP1 protein expression and activity. LS-180V intestinal carcinoma cells were exposed for 3 days to 1±100 mM

Development of vincristine resistance an

Development of vincristine resistance and increased sensitivity to cyclosporin A and verapamil in the human U-937 lymphoma cell line without overexpression of the 170-KDa P-glycoprotein

✍ Johan Botling; Gunnar Liminga; Rolf Larsson; Peter Nygren; Kenneth Nilsson 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 767 KB

A vincristine (vcr)-resistant subline of the human histiocytic lymphoma cell line U-937 (U-937-vcr) has been established and characterized with respect to its phenotypic features, including growth rate, surface marker expression and ability to respond to differentiation-inducing agents. The sensitiv

Doxorubicin induces expression of multid

Doxorubicin induces expression of multidrug resistance-associated protein 1 in human small cell lung cancer cell lines by the c-jun N-terminal kinase pathway

✍ Chie Shinoda; Muneharu Maruyama; Takashi Fujishita; Junichi Dohkan; Hirofumi Oda 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 646 KB

Multidrug resistance (MDR) is a major impediment to successful chemotherapy for lung cancer. Overexpression of multidrug resistance-associated protein 1 (MRP1) appears to be involved in MDR development in lung cancer cells. A number of chemotherapeutic agents including doxorubicin (DOX) were reporte