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Overexpression of Multidrug Resistance Protein Gene in Human Cancer Cell Lines Selected for Drug Resistance to Epipodophyllotoxins

โœ Scribed by Koike, Koji ;Abe, Tatsuya ;Hisano, Terumasa ;Kubo, Takeshi ;Wada, Morimasa ;Kohno, Kimitoshi ;Kuwano, Michihiko


Book ID
108581239
Publisher
Wiley (Blackwell Publishing)
Year
1996
Tongue
English
Weight
495 KB
Volume
87
Category
Article
ISSN
0910-5050

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Annamycin circumvents resistance mediate
โœ Roman Perez-Soler; Nouri Neamati; Yiyu Zou; Erasmus Schneider; L. Austin Doyle; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 144 KB ๐Ÿ‘ 2 views

Annamycin (Ann) is a highly lipophilic anthracycline antibiotic that has been shown to circumvent MDR-1 both in vitro and in vivo. A liposomal formulation of Ann is currently in phase I clinical trials. The multidrug resistance-associated protein (MRP) has been found to be over-expressed in some hum