Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells
โ Scribed by Shuji Hasegawa; Ken Taniguchi; Akira Yokomizo; Takashi Kuwano; Mayumi Ono; Temaki Mori; Shigeaki Hori; Kimitoshi Kohno; Michihiko Kuwano
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- French
- Weight
- 671 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
MRP has been identified as another multidrug-resistance (MDR) gene and may be involved in an alternative MDR mechanism in some solid tumors. We investigated the expres- sion of M R P mRNA in multidrug-resistant KB sublines (KB-8-5, KB-CZ, C -W and C A I to), human non-small-cell lung carcinomas (NSC
The present study characterized the response of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP1) to chronic ritonavir (RIT) exposure by assessing increases in P-gp and MRP1 protein expression and activity. LS-180V intestinal carcinoma cells were exposed for 3 days to 1ยฑ100 mM