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Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells

✍ Scribed by Walter Berger; Erich Hauptmann; Leonilla Elbling; Monika Vetterlein; Eva M. Kokoschka; Michael Micksche


Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
104 KB
Volume
71
Category
Article
ISSN
0020-7136

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✍ Walter Berger; Leonilla Elbling; Erich Hauptmann; Michael Micksche πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 224 KB πŸ‘ 2 views

Human non-small-cell lung cancer (NSCLC) is considered to be a chemotherapy-refractory malignancy. The underlying mechanisms remain rather obscure. The multidrug resistanceassociated protein (MRP), mediating a multidrug resistance (MDR) phenotype, has been reported to be overexpressed in several dru