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P53, cyclin D1 and Rb genes expression changes in esophageal squamous cell carcinoma in iran

โœ Scribed by Moghaddam, Seyed Javad Mirhassani; Daneshmand, Mohammad Ali; Aghakhani, Arezoo; Edrissian, Mohammad Omid; Zali, Mohammad Reza


Book ID
123369864
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
181 KB
Volume
124
Category
Article
ISSN
0016-5085

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Loss of heterozygosity at 4 tumor-suppressor gene loci (pS3, apc, mcc and Rb) was investigated using polymerase chain reactions, in 49 esophageal squamous-cell carcinoma specimens from patients who had undergone curative resection. Mutations in the p53 gene within exons 5 to 8 were also examined. LO