P53, cyclin D1 and Rb genes expression changes in esophageal squamous cell carcinoma in iran
โ Scribed by Moghaddam, Seyed Javad Mirhassani; Daneshmand, Mohammad Ali; Aghakhani, Arezoo; Edrissian, Mohammad Omid; Zali, Mohammad Reza
- Book ID
- 123369864
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 181 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0016-5085
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Loss of heterozygosity at 4 tumor-suppressor gene loci (pS3, apc, mcc and Rb) was investigated using polymerase chain reactions, in 49 esophageal squamous-cell carcinoma specimens from patients who had undergone curative resection. Mutations in the p53 gene within exons 5 to 8 were also examined. LO