𝔖 Bobbio Scriptorium
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P405 - HLA-B27 transgenic mice: An animal model of human arthropathies

✍ Scribed by Chopin Martine; Plichtová Rita; Pla Marika


Book ID
116114812
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
126 KB
Volume
47
Category
Article
ISSN
0198-8859

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Linkage studies indicate close associations of certain HLA alleles with autoimmune diseases. To better understand how specific HLA alleles are related to disease pathogenesis, we have generated an HLA DR3/DQ2 transgenic mouse utilizing a 550-kb yeast artificial chromosome (YAC) construct containing