Characterization of HLA DR3/DQ2 transgen
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Dan Chen; Roanna Ueda; Fiona Harding; Namrata Patil; Yifan Mao; Carole Kurahara;
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Article
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2003
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John Wiley and Sons
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English
β 472 KB
Linkage studies indicate close associations of certain HLA alleles with autoimmune diseases. To better understand how specific HLA alleles are related to disease pathogenesis, we have generated an HLA DR3/DQ2 transgenic mouse utilizing a 550-kb yeast artificial chromosome (YAC) construct containing