Mice transgenic for reduced folate carrier: an animal model of Down syndrome?
✍ Scribed by Joachim Höger; David Patterson; Harald Höger; Ki-Shuk Shim; Hermann Bubna-Littitz; Gert Lubec
- Book ID
- 106221649
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 191 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0939-4451
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The transgenic mouse rasH2 line, in which the mouse carries the human c-Ha-ras gene under the control of its own enhancer and promoter, has been proposed as one of the alternative short-term models for carcinogenicity testing. To apply this purpose, we have produced a genetically homogeneous populat
Carcinoembryonic antigen (CEA) is a tumor marker for the most common forms of adenocarcinomas. We have previously described C57BL/6 mice transgenic for the complete human CEA gene. Compared with humans, these mice reveal a conserved spatiotemporal CEA expression pattern. To establish animal models f