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The Absence of Human β2-microglobulin Increasesthe Occurrence of Ankylosing Enthesopathy in HLA-B27 Transgenic Mice

✍ Scribed by Pla, M.; Chopin, M.; Plichtova, R.; Urbero, B.


Book ID
121544063
Publisher
Springer
Year
1996
Tongue
English
Weight
738 KB
Volume
15
Category
Article
ISSN
0770-3198

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Expression of HLA-B27 in transgenic mice
✍ Chery L. Nickerson-Nutter; Chella S. David 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 360 KB

The HLA-B27 transgene was introduced into mice of the B10 background with various H-2 haplotypes. High levels of B27 antigen were detected on the surface of peripheral-blood lymphocytes from mice homozygous for the H-2b, H-2f, H-2s, H-2p, H-2r and H-2k haplotypes. In contrast, cell-surface expressio