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P3-206: Genetic variability at the progranulin locus contributes to risk for Alzheimer's disease

✍ Scribed by Brouwers, Nathalie; Sleegers, Kristel; Engelborghs, Sebastiaan; Maurer-Stroh, Sébastian; Gijselinck, Ilse; van der Zee, Julie; Pickut, Barbara; Van den Broeck, Marleen; Mattheijssens, Maria; Peeters, Karin; Schymkowitz, Joost; Rousseau, Frédéric; Martin, Jean-Jacques; Cruts, Marc; De Deyn, Peter Paul; Van Broeckhoven, Christine


Book ID
123107385
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
4
Category
Article
ISSN
1552-5260

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✍ Veerle Bogaerts; Karen Nuytemans; Joke Reumers; Philippe Pals; Sebastiaan Engelb 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB

## Communicated by Michael Dean In one genetic study, the high temperature requirement A2 (HTRA2) mitochondrial protein has been associated with increased risk for sporadic Parkinson disease (PD). One missense mutation, p.Gly399Ser, in its C-terminal PDZ domain (from the initial letters of the pos