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p16(MTS-1/CDKN2/INK4a) in Cancer Progression

✍ Scribed by James W. Rocco; David Sidransky


Book ID
115603937
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
179 KB
Volume
264
Category
Article
ISSN
0014-4827

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The p16 INK4A /CDKN2/MTS1 gene encodes a specific inhibitor of cyclin-dependent kinases (CDKs) 4 and 6. This study investigates p16 INK4A gene status and expression in mesenchymal tumours, in particular soft tissue sarcomas (STSs). Employing non-radioactive polymerase chain reaction-single strand co