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DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours

✍ Scribed by Woodcock, D M; Linsenmeyer, M E; Doherty, J P; Warren, W D

Book ID
110000910
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
141 KB
Volume
79
Category
Article
ISSN
0007-0920

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## Abstract Among the identified factors involved in malignant transformation, abnormal methylation of the __CDKN2A/p16__^__INK4a__^ gene promoter has been described as an early event, particularly in bronchial cell cancerization. Precancerous bronchial lesions (__n__ = 70) prospectively sampled du