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Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia

✍ Scribed by Iravani, M; Dhat, R; Price, C M


Book ID
110061006
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
367 KB
Volume
15
Category
Article
ISSN
0950-9232

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Immunohistochemistry was used to analyze samples of 40 newly diagnosed childhood acute lymphoblastic leukemias (ALL) for their expression of cyclins (D1, E, A), cyclindependent kinases (cdk2, cdk4) and tumor-suppressor genes (pRb, p16 INK4A ), in order to discover whether or not the expression of th