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Methylation of the p16INK4a promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells

โœ Scribed by Darbro, B W; Lee, K M; Nguyen, N K; Domann, F E; Klingelhutz, A J


Book ID
110070744
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
358 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1ฮฑ for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci