✦ LIBER ✦

p16INK4A/MTS1/CDKN2 – das „Melanomgen”? Stand der Forschung und Ausblick

✍ Scribed by Thomas Bogenrieder; Michael Landthaler; Wilhelm Stolz

Publisher: Springer
Year: 1998
Tongue: German
Weight: 450 KB
Volume: 49
Category: Article
ISSN: 0017-8470
DOI: 10.1007/s001050050706

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

No p16INK4A/CDKN2/MTS1 mutations indepen

No p16INK4A/CDKN2/MTS1 mutations independent of p53 status in soft tissue sarcomas

✍ Meye, Axel; Würl, Peter; Hinze, Raoul; Berger, Dieter; Bache, Matthias; Schmidt, 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

The p16 INK4A /CDKN2/MTS1 gene encodes a specific inhibitor of cyclin-dependent kinases (CDKs) 4 and 6. This study investigates p16 INK4A gene status and expression in mesenchymal tumours, in particular soft tissue sarcomas (STSs). Employing non-radioactive polymerase chain reaction-single strand co

Growth arrest and suppression of tumorig

Growth arrest and suppression of tumorigenicity of bladder carcinoma cell lines induced by the P16/CDKN2 (p16INK4A, MTS1) gene and other loci on human chromosome 9

✍ Qiang Wu; Laura Possati; Marco Montesi; Francesca Gualandi; Paola Rimessi; Crist 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 889 KB

## Wild -type P16ICDKNZ MTSI) cDNA, directed by the cytomegalovirus (CMV) immediate early promoter, was transfected into RT4 and RTI I 2 bladder-carcinoma cell lines bearing a mutated endogenous P16ICDKNZ gene and lacking endogenous P 16lCDKN2 respectively. In both cases, only transfected clones w