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P16INK4Gene Mutations Are Relatively Frequent in Ampullary Carcinomas

✍ Scribed by Imai, Yasuo ;Tsurutani, Naomi ;Oda, Hideaki ;Nakatsuru, Yoko ;Inoue, Tohru ;Ishikawa, Takatoshi


Book ID
108581345
Publisher
Wiley (Blackwell Publishing)
Year
1997
Tongue
English
Weight
522 KB
Volume
88
Category
Article
ISSN
0910-5050

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## Background: It has been suggested that cyclin-dependent kinase inhibitors (cdkis), including p16 and p15, are tumor suppressor genes. alterations of cdkis have been found in most types of cancer. however, little is known about the status of p16 and p15 genes, including methylation of the promote