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p16INK4a Gene Alterations Are Frequent in Lesions of Mycosis Fungoides

✍ Scribed by Inmaculada C. Navas; Pablo L. Ortiz-Romero; Raquel Villuendas; Pedro Martínez; Carmen García; Enrique Gómez; Jose L. Rodriguez; Domingo García; Francisco Vanaclocha; Luis Iglesias; Miguel A. Piris; Patrocinio Algara


Book ID
117022497
Publisher
American Society for Investigative Pathology
Year
2000
Tongue
English
Weight
456 KB
Volume
156
Category
Article
ISSN
0002-9440

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Alterations of p16INK4A and p15INK4B gen
✍ Young Y. Lee; Shin H. Kang; Jin Y. Seo; Chul W. Jung; Kuhn U. Lee; Kuk J. Choe; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 1 views

## Background: It has been suggested that cyclin-dependent kinase inhibitors (cdkis), including p16 and p15, are tumor suppressor genes. alterations of cdkis have been found in most types of cancer. however, little is known about the status of p16 and p15 genes, including methylation of the promote