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P-287 Aberrant DNA methylation of the hDAB2IP gene in the promoter region in lung carcinomas

✍ Scribed by Yano, Masaaki; Toyooka, Shinichi; Tsukuda, Kazunori; Dote, Hideaki; Aoe, Motoi; Chen, Hong; Hsieh, Jer-Tsong; Minna, John D.; Gazdar, Adi F.; Shimizu, Nobuyoshi


Book ID
118571987
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
374 KB
Volume
41
Category
Article
ISSN
0169-5002

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Aberrant promoter methylation of human D
✍ Masaaki Yano; Shinichi Toyooka; Kazunori Tsukuda; Hideaki Dote; Mamoru Ouchida; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 767 KB

## Abstract The human DOC‐2/DAB2 interactive protein gene (__hDAB2IP__) is a novel member of the Ras GTPase‐activating gene family that is known to act as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers. We established previously a methylation‐specific PCR (