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Aberrant promoter methylation of the TPEF gene in esophageal squamous cell carcinoma

โœ Scribed by B.-J. Zhao; S.-N. Tan; Y. Cui; D.-G. Sun; Xu Ma


Book ID
108981077
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
181 KB
Volume
21
Category
Article
ISSN
1120-8694

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## Abstract Previous studies on esophageal squamous cell carcinoma (ESCC) indicated that it contains much dysregulation of microRNAs (miRNAs). DNA hypermethylation in the miRNA 5โ€ฒ regulatory region is a mechanism that can account for the downregulation of miRNA in tumors (Esteller, N Engl J Med 200