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Aberrant promoter methylation and reduced expression of p16 gene in esophageal squamous cell carcinoma from Kashmir valley: a high-risk area

✍ Scribed by Irfana Salam; Showket Hussain; Mohammad Muzaffar Mir; Nazir Ahmad Dar; Safiya Abdullah; Mushtaq Ahmad Siddiqi; Riyaz Ahmad Lone; Showkat Ahmad Zargar; Shashi Sharma; Suresh Hedau; Seemi Farhat Basir; Alok Chandra Bharti; Bhudev C. Das

Publisher: Springer
Year: 2009
Tongue: English
Weight: 235 KB
Volume: 332
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-009-0173-7

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## Abstract Investigation of potential association of SNPs (G870A, rs9344; G1722C, rs678653) of cyclin D1 gene (__CCND1__) with susceptibility to esophageal squamous cell carcinoma (ESCC) in Kashmir valley (India). The study included 302 subjects comprising 151 ESCC cases and 151 controls. PCR‐RFLP