Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary gland
โ Scribed by TSUTOMU DAA; KENJI KASHIMA; YOSHIYUKI KONDO; NAOMI YADA; MASASHI SUZUKI; SHIGEO YOKOYAMA
- Book ID
- 109343770
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 149 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0365-5555
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Cyclin-dependent kinase inhibitors play a significant role in cell cycle progression and in cellular differentiation and their expression is regulated in different cellular settings. GC-rich regions in the promoter sequences of the cyclin-dependent kinase inhibitor genes p15INK4B and p21CIP1/WAF1 me
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