Oxygen-17 NMR studies of carbonic anhydrase
โ Scribed by Rose, K. D.; Bryant, R. G.
- Book ID
- 127290848
- Publisher
- American Chemical Society
- Year
- 1980
- Tongue
- English
- Weight
- 557 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
## Abstract Natural abundance ^17^O and ^13^C NMR spectra for eleven diarylketenes are reported. ^17^O shifts show invariance with __para__ substitution and a shielding due to __ortho__ substitution. A buttressing effect is observed for bis(2,3,4,5,6โpentamethylphenyl)ketene. A comparison between k
Fluorine and nitrogen-15 NMR experiments are described which show that 3,5-diรuorobenzenesulfonamide binds to human carbonic anhydrase I in a 1 : 1 complex, that the bound inhibitor is present as an anion and that the aromatic ring of the inhibitor undergoes rapid rotation in the complex in spite of