Oxidation of dithiols by flavopapain
โ Scribed by Fried, Herbert E.; Kaiser, E. T.
- Book ID
- 126323375
- Publisher
- American Chemical Society
- Year
- 1981
- Tongue
- English
- Weight
- 433 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
The cysteine-bridged macrocycles, 22-32-membered cyclic dimers could be synthesized with a high reagent concentration (1 M) in excellent yields by the oxidation of the cysteine-based compounds having dithiol groups.
compounds, and by the synthesis of (16) (yield 66%, m.p. 77ยฐC) we could show that long alkyl groups hardly hinder this type of coupling at all.
## Abstract Rates of oxidation of various dithiols with 3โmethyllumiflavin to afford the corresponding cyclic disulfides have been examined at various pH values in 30% aqueous ethanol at 30ยฐC. 1,3โPropanedithiol, which affords 1,2โdithiolane, has been found to be the most reactive among several dit