Efficient synthesis of macrocycles by oxidation of cysteine-based dithiols

✍ Scribed by Hiroto Kudo; Fumio Sanda; Takeshi Endo

• Book ID: 104231633
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 87 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01584-2

✦ Synopsis

The cysteine-bridged macrocycles, 22-32-membered cyclic dimers could be synthesized with a high reagent concentration (1 M) in excellent yields by the oxidation of the cysteine-based compounds having dithiol groups.