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Overcoming resistance to EGFR inhibitor in head and neck cancer: A review of the literature

✍ Scribed by Guilherme Rabinowits; Robert I. Haddad


Book ID
119339292
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
177 KB
Volume
48
Category
Article
ISSN
1368-8375

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Mechanisms of resistance to EGFR inhibit
✍ Jonathan B. Cooper; Ezra Eddy Wyssam Cohen πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

## Abstract Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that activates multiple signaling pathways, including phosphatidylinositol‐3‐kinase/v‐AKT murine thymoma viral oncogene homolog protein (Akt), has long been a target of novel therapies. Despite universal EGFR expression