## Abstract ^1^H magnetic resonance spectroscopic imaging has been used to obtain metabolite maps of the rat brain. The spin‐echo‐based technique has been evaluated with respect to water and lipid suppression and sensitivity. Metabolite maps were constructed for choline. creatine + phosphocreatine,
Out-and-in spiral spectroscopic imaging in rat brain at 7 T
✍ Scribed by Bassem Hiba; Bérengère Faure; Laurent Lamalle; Michel Décorps; Anne Ziegler
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 569 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
With standard spectroscopic imaging, high spatial resolution is achieved at the price of a large number of phase‐encoding steps, leading to long acquisition times. Fast spatial encoding methods reduce the minimum total acquisition time. In this article, a k‐space scanning scheme using a continuous series of growing and shrinking, or “out‐and‐in,” spiral trajectories is implemented and the feasibility of spiral spectroscopic imaging for animal models at high B~0~ field is demonstrated. This method was applied to rat brain at 7 T. With a voxel size of about 8.7 μl (as calculated from the point‐spread function), a 30 × 30 matrix, and a spectral bandwidth of 11 kHz, the minimum scan time was 9 min 20 sec for a signal‐to‐noise ratio of 7.1 measured on the N‐acetylaspartate peak. Magn Reson Med 50:1127–1133, 2003. © 2003 Wiley‐Liss, Inc.
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