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Detection of brain glutamate and glutamine in spectroscopic images at 4.1 T

✍ Scribed by Graeme F. Mason; Jullie W. Pan; Steven L. Ponder; Donald B. Twieg; Gerald M. Pohost; Hoby P. Hetherington

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 420 KB
Volume: 32
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910320121

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Brain glutamate and glutamine were detected in healthy human volunteers in spectroscopic images with a nominal voxel size of 2.25 cm^3^ at an echo time of 15 ms. Due to the increased frequency separation and simplification of J‐coupling patterns, the separate detection of brain glutamate and glutamine at short echo times was possible. Creatine, choline, and N‐acetylaspartate with other N‐acetylated compounds were also detected. The ratios of the metabolite resonance intensities were in agreement with previously published values.

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