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Ototoxicity, nephrotoxicity and pharmacokinetics of cisplatin and its monohydrated complex in the guinea pig

✍ Scribed by Andreas Ekborn; Annika Lindberg; Göran Laurell; Inger Wallin; Staffan Eksborg; Hans Ehrsson

Publisher
Springer
Year
2003
Tongue
English
Weight
224 KB
Volume
51
Category
Article
ISSN
0344-5704

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✍ Anubha Gupta; Margareta Hammarlund-Udenaes; Pierre Chatelain; Roy Massingham; E. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB 👁 2 views

## Abstract __Purpose__. To characterize the pharmacokinetics of cetirizine enantiomers in the guinea pig including protein binding in both the guinea pig and human plasma. __Methods__. Plasma concentrations of cetirizine enantiomers in the guinea pig were determined using a LC‐MS/MS method after