✦ LIBER ✦

The pharmacokinetics of azlocillin in the perilymph of guinea pigs and otitis media

✍ Scribed by P. Federspil

Publisher: Springer-Verlag
Year: 1982
Tongue: English
Weight: 564 KB
Volume: 10
Category: Article
ISSN: 0300-8126
DOI: 10.1007/bf01640678

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereoselective pharmacokinetics and met

Stereoselective pharmacokinetics and metabolism of flobufen in guinea pigs

✍ František Trejtnar; Radim Král; Petr Pávek; Vladimír Wsól 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB

## Abstract Stereoselective aspects of pharmacokinetics and metabolism of a chiral nonsteroidal antiinflammatory drug, flobufen, 4‐(2′, 4′‐difluorobiphenyl‐4‐yl)‐2‐methyl‐4‐oxobutanoic acid, were studied in male guinea pigs after p.o. administration of racemic flobufen (__rac__‐flobufen) at a dose

Effect of itraconazole on the pharmacoki

Effect of itraconazole on the pharmacokinetics of digoxin in guinea pigs

✍ Kazuyo Nishihara; Junko Hibino; Hajime Kotaki; Yasufumi Sawada; Tatsuji Iga 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 2 views

The effect of itraconazole (ITZ) on the pharmacokinetics of digoxin (DGX) was investigated in guinea pigs. The plasma concentrations of DGX in guinea pigs following treatment with ITZ (20 mg/kg intraperitoneally (i.p.)) after intravenous (i.v.) administration of DGX (0.125 mg/kg) were significantly

Pharmacodynamics and pharmacokinetics of

Pharmacodynamics and pharmacokinetics of haloperidol and reduced haloperidol in guinea pigs

✍ Wen-Ho Chang; Shu-Swei Jaw; Ho-Sheng Wu; Lacan Tsay; Eng-Kung Yeh 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 322 KB

Striatal homovanillic acid (HVA) levels and drug concentrations in striatum and plasma were examined in guinea pigs after acute and subchronic administrations of haloperidol (HAL) and reduced HAL (RHAL). HVA and drug levels were measured by high performance liquid chromatography with electrochemical

Nitric oxide synthase activity and nitri

Nitric oxide synthase activity and nitric oxide level in erythrocytes of guinea pigs with experimental otitis media with effusion

✍ Adnan Yilmaz; Celil Uslu; Mehmet Akyuz 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB 👁 1 views

Free radicals have been implicated in the pathogenesis of an increasing number of disease and inflammatory states. They may cause cell and tissue damage by chemical modification of proteins, carbohydrates, nucleotides and lipids. Under physiological conditions free radicals are parts of normal regul

Effect of zixoryn on the pharmacokinetic

Effect of zixoryn on the pharmacokinetics of antipyrine in intact and sensitized guinea pigs

✍ T. G. Khlopushina; A. V. Krinskaya; L. P. Kovalenko; V. P. Zherdev; A. V. Val'dm 📂 Article 📅 1991 🏛 Springer US 🌐 English ⚖ 226 KB

Stereoselective pharmacokinetics of ceti

Stereoselective pharmacokinetics of cetirizine in the guinea pig: role of protein binding

✍ Anubha Gupta; Margareta Hammarlund-Udenaes; Pierre Chatelain; Roy Massingham; E. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB 👁 2 views

## Abstract __Purpose__. To characterize the pharmacokinetics of cetirizine enantiomers in the guinea pig including protein binding in both the guinea pig and human plasma. __Methods__. Plasma concentrations of cetirizine enantiomers in the guinea pig were determined using a LC‐MS/MS method after