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Orally active esters of cephalosporin antibiotics. 3. Synthesis and biological properties of aminoacyloxymethyl esters of 7-[D-(-)-mandelamido]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-3-cephem-4-carboxylic acid

✍ Scribed by Wheeler, W. J.; Preston, D. A.; Wright, W. E.; Huffman, G. W.; Osborne, H. E.; Howard, D. P.

Book ID
127328606
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
661 KB
Volume
22
Category
Article
ISSN
0022-2623

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Synthesis of 7-D-mandel-Ξ²-14C-amino-3-{[
Synthesis of 7-D-mandel-Ξ²-14C-amino-3-{[(1-methyl-1H-tetrazol-5-yl)-thio]methyl}-3-cephem-4-carboxylic acid (cefamandole-14C)
✍ H. Minato; T. Nagasaki; Y. Katsuyama; M. Hamada; R. Kiritani πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 French βš– 272 KB πŸ‘ 1 views

Cefamandole, 7-D-mandelamino-3-{ [(l-methyl-lH-tetrazo1-5-yl)-thio]methyl}-3-cephem-4-carboxylic acid (I), is a new semisynthetic, parenteral cephalosporin antibiotic with a broad antibacterial spectrum, synthesized by the Lilly Research Laboratories.