## Abstract For Abstract see ChemInform Abstract in Full Text.
Orally active amino functionalized antimalarial 1,2,4-trioxanes
โ Scribed by Chandan Singh; Heetika Malik; Sunil K Puri
- Book ID
- 108073146
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 168 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0960-894X
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๐ SIMILAR VOLUMES
The three dihydronaphtho[l,2,4]trioxines e l l have been synthesized and two of them converted to the five carbamate and ester derivatives 12-16 (Schemes I and 2). The resulting new trioxanes together with two already known and ascaridole (7) were tested for antimalarial activity against the sensiti
Geraniol, an abundantly available naturally occurring allylic alcohol, has been used as a starting material to prepare a series of 6-[a-(3 0 -aryl-3 0 -hydroxypropyl)vinyl]-1,2,4-trioxanes. Some of these novel trioxanes have shown very promising antimalarial activity against multi-drug resistant Pla