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Orally Active Amino Functionalized Antimalarial 1,2,4-Trioxanes.

โœ Scribed by Chandan Singh; Heetika Malik; Sunil K. Puri

Publisher
John Wiley and Sons
Year
2004
Weight
90 KB
Volume
35
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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Synthesis of New 1,2,4-Trioxanes and the
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โœ Charles W. Jefford; Ernest C. McGoran; John Boukouvalas; Geoffrey Richardson; Br ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 497 KB

The three dihydronaphtho[l,2,4]trioxines e l l have been synthesized and two of them converted to the five carbamate and ester derivatives 12-16 (Schemes I and 2). The resulting new trioxanes together with two already known and ascaridole (7) were tested for antimalarial activity against the sensiti