Ontogenic aspects of cisplatin-induced nephrotoxicity in rats
β Scribed by B.H. Ali; M. Al-Moundhri; M. Tageldin; I.S. Al Husseini; Mohmed A. Mansour; A. Nemmar; M.O. Tanira
- Book ID
- 116462552
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 377 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0278-6915
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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r